RGL2

Across TCGA cell cohorts, RGL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,289 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RGL2-associated GO terms across cancer lineages are Sperm motility, Cilium or flagellum-dependent cell motility, and Flagellated sperm motility. Each is linked with RGL2 in more than 17 cancer types. Because this analysis shows association rather than direction, both RGL2-to-partner and partner-to-RGL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by RGL2-low versus RGL2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGL2→partner) and Y-score (partner→RGL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Sperm motility →	-0.110	-1.644	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.101	-1.024	<.001	<.001	3	18
BREAST	Flagellated sperm motility →	-0.110	-1.644	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.101	-1.024	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.103	-1.024	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Vesicle-mediated transport to the plasma membrane →	+0.061	+0.896	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,289 associations by consensus.

Sperm motility by RGL2 expression — BREAST

Explore this box plot interactively →