RGL1

Across TCGA cell cohorts, RGL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,360 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RGL1-associated GO terms across cancer lineages are Positive regulation of epithelial to mesenchymal transition, Protein localization to lysosome, and Process utilizing autophagic mechanism. Each is linked with RGL1 in more than 11 cancer types. Because this analysis shows association rather than direction, both RGL1-to-partner and partner-to-RGL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of epithelial to mesenchymal transition grouped by RGL1-low versus RGL1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGL1→partner) and Y-score (partner→RGL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Positive regulation of epithelial to mesenchymal transition →	+0.088	+1.029	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Protein localization to lysosome →	+0.072	+0.786	.003	.005	3	11
LIVER	Process utilizing autophagic mechanism →	+0.038	+1.275	.001	.005	3	11
LIVER	Autophagy →	+0.038	+1.275	.001	.005	3	11
BREAST	Regulation of intracellular transport →	+0.052	+1.363	<.001	<.001	3	10
SOFT_TISSUE	Regulation of transforming growth factor beta receptor signaling pathway →	+0.046	+1.256	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,360 associations by consensus.

Positive regulation of epithelial to mesenchymal transition by RGL1 expression — CNS

Explore this box plot interactively →