RGCC

Across TCGA patient cohorts, RGCC protein abundance is significantly associated with the RNA expression of many other genes, with 16,581 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RGCC-associated genes across cancer lineages are CNRIP1, IRAG1, and STARD9. Each is linked with RGCC in more than 6 cancer types. Because this analysis shows association rather than direction, both RGCC-to-partner and partner-to-RGCC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGCC versus CNRIP1 in BRCA, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGCC→partner) and Y-score (partner→RGCC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNRIP1 →	+0.671	+0.469	<.001	<.001	3	7
GBM	IRAG1 →	+1.116	+0.720	<.001	<.001	3	7
LSCC	STARD9 →	+0.709	+0.387	<.001	.001	3	6
UCEC	NEXN →	+1.303	+0.522	<.001	<.001	3	6
BRCA	FILIP1L →	+1.159	+0.640	<.001	<.001	3	6
PDAC	COL8A2 →	+1.141	+0.516	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,581 associations by consensus.

RGCC vs CNRIP1 — BRCA

Explore this scatter interactively →