RGCC

Across TCGA cell cohorts, RGCC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,796 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RGCC-associated GO terms across cancer lineages are Negative regulation of protein polymerization, Negative regulation of transforming growth factor beta production, and Complement receptor mediated signaling pathway. Each is linked with RGCC in more than 7 cancer types. Because this analysis shows association rather than direction, both RGCC-to-partner and partner-to-RGCC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein polymerization grouped by RGCC-low versus RGCC-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGCC→partner) and Y-score (partner→RGCC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of protein polymerization →	+0.116	+1.888	<.001	<.001	3	8
LARGE_INTESTINE	Negative regulation of transforming growth factor beta production →	+0.201	+2.320	<.001	<.001	3	7
BLOOD_Leukemia	Complement receptor mediated signaling pathway →	-0.306	-1.335	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Motile cilium assembly →	-0.052	-2.096	<.001	<.001	3	7
STOMACH	Response to unfolded protein →	+0.091	+1.103	<.001	.002	3	7
PANCREAS	Positive regulation of matrix metallopeptidase secretion →	-0.188	-1.534	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,796 associations by consensus.

Negative regulation of protein polymerization by RGCC expression — PANCREAS

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