Across TCGA cell cohorts, RFX8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,933 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RFX8-associated GO terms across cancer lineages are Response to acetaldehyde, Cellular response to acetaldehyde, and Positive regulation of cell-substrate junction organization. Each is linked with RFX8 in more than 8 cancer types. Because this analysis shows association rather than direction, both RFX8-to-partner and partner-to-RFX8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX8→partner) and Y-score (partner→RFX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to acetaldehyde →	+0.266	+1.241	.002	.008	3	9
BONE	Cellular response to acetaldehyde →	+0.266	+1.241	.002	.008	3	9
BONE	Positive regulation of cell-substrate junction organization →	+0.160	+1.839	<.001	<.001	3	8
BONE	Fibrinolysis →	+1.683	+1.759	<.001	<.001	3	8
BREAST	Establishment of epithelial cell apical/basal polarity →	+0.180	+0.592	<.001	.008	3	8
SOFT_TISSUE	Regulation of protein processing →	+0.213	+1.437	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,933 associations by consensus.

Exploration

RFX8 survival (RNA) · tumor vs normal (RNA) · all RFX8 data types