RFX7

Across TCGA cell cohorts, RFX7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,396 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RFX7-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Negative regulation of gene expression, epigenetic, and Heterochromatin formation. Each is linked with RFX7 in more than 18 cancer types. Because this analysis shows association rather than direction, both RFX7-to-partner and partner-to-RFX7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by RFX7-low versus RFX7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX7→partner) and Y-score (partner→RFX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epigenetic regulation of gene expression →	+0.113	+1.113	<.001	<.001	3	19
BONE	Negative regulation of gene expression, epigenetic →	+0.074	+0.642	<.001	<.001	3	19
BONE	Heterochromatin formation →	+0.071	+0.642	<.001	<.001	3	18
BLOOD_Lymphoma	Nuclear transport →	+0.083	+1.177	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	RNA localization →	+0.100	+1.340	<.001	<.001	3	18
BLOOD_Lymphoma	Nucleocytoplasmic transport →	+0.083	+1.156	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,396 associations by consensus.

Epigenetic regulation of gene expression by RFX7 expression — BONE

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