RFX5

Across TCGA patient cohorts, RFX5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,112 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RFX5-associated proteins across cancer lineages are ADAR, RPRD2, and GATAD2B. Each is linked with RFX5 in more than 8 cancer types. Because this analysis shows association rather than direction, both RFX5-to-partner and partner-to-RFX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFX5 versus ADAR in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX5→partner) and Y-score (partner→RFX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADAR →	+0.348	+0.553	<.001	.001	3	9
BRCA	RPRD2 →	+0.335	+0.699	<.001	<.001	3	7
HNSC	GATAD2B →	+0.340	+0.791	<.001	.001	3	7
CCRCC	PSMB5 →	-0.481	-0.522	<.001	<.001	3	6
OV	CD74 →	+0.679	+0.610	.001	<.001	3	6
GBM	MTA2 →	+0.370	+0.396	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,112 associations by consensus.

RFX5 vs ADAR — BRCA

Explore this scatter interactively →