RFX5

Across TCGA patient cohorts, RFX5 protein abundance is significantly associated with the RNA expression of many other genes, with 13,733 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RFX5-associated genes across cancer lineages are BTN2A2, HCP5, and SEPTIN1. Each is linked with RFX5 in more than 6 cancer types. Because this analysis shows association rather than direction, both RFX5-to-partner and partner-to-RFX5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFX5 versus BTN2A2 in HNSC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX5→partner) and Y-score (partner→RFX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BTN2A2 →	+0.744	+0.413	<.001	<.001	3	7
GBM	HCP5 →	+0.996	+0.269	.001	<.001	3	7
HNSC	SEPTIN1 →	+0.819	+0.391	<.001	<.001	3	7
UCEC	BTN3A3 →	+1.026	+0.272	<.001	.002	3	6
HNSC	HILPDA →	-1.065	-0.444	<.001	<.001	3	6
GBM	COQ10A →	+0.427	+0.316	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,733 associations by consensus.

RFX5 vs BTN2A2 — HNSC

Explore this scatter interactively →