RFX4

Across TCGA patient cohorts, RFX4 protein abundance is significantly associated with the RNA expression of many other genes, with 4,148 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RFX4-associated genes across cancer lineages are GGT1, CRYBB3, and TTC28. Each is linked with RFX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RFX4-to-partner and partner-to-RFX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFX4 versus GGT1 in GBM, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX4→partner) and Y-score (partner→RFX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GGT1 →	+0.176	+0.367	.001	<.001	3	1
GBM	CRYBB3 →	+0.483	+0.336	.001	.001	3	1
GBM	TTC28 →	+0.310	+0.273	.004	<.001	3	1
GBM	CBY1 →	+0.361	+0.359	.002	.002	3	1
GBM	ABHD4 →	+0.238	+0.263	.008	.008	3	1
GBM	RBM23 →	+0.288	+0.401	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,148 associations by consensus.

RFX4 vs GGT1 — GBM

Explore this scatter interactively →