RFX1

Across TCGA patient cohorts, RFX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,888 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RFX1-associated proteins across cancer lineages are ZZEF1_S1464, VPS9D1_S116, and BUB3. Each is linked with RFX1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RFX1-to-partner and partner-to-RFX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFX1 versus ZZEF1_S1464 in LSCC, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX1→partner) and Y-score (partner→RFX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZZEF1_S1464 →	-0.484	-0.315	.003	.001	3	3
LUAD	VPS9D1_S116 →	-0.591	-0.374	.001	.001	3	3
GBM	BUB3 →	+0.248	+0.381	<.001	.001	3	3
LSCC	C1orf35_S217 →	+0.726	+0.389	.008	<.001	2	4
CCRCC	CCNY_S83 →	-0.374	-0.424	<.001	.007	3	3
PDAC	DNAJC1 →	-0.386	-0.301	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,888 associations by consensus.

RFX1 vs ZZEF1_S1464 — LSCC

Explore this scatter interactively →