RFX1

Across TCGA cell cohorts, RFX1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,891 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RFX1-associated genes across cancer lineages are ZC3H14, ABCD4, and PPP4R3A. Each is linked with RFX1 in more than 11 cancer types. Because this analysis shows association rather than direction, both RFX1-to-partner and partner-to-RFX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFX1 versus ZC3H14 in BONE, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFX1→partner) and Y-score (partner→RFX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	ZC3H14 →	+0.747	+0.564	.007	<.001	3	12
BLOOD_Leukemia	ABCD4 →	+0.847	+0.483	<.001	.001	2	9
PANCREAS	PPP4R3A →	+0.577	+0.639	.004	.001	3	7
OESOPHAGUS	MTA1 →	+1.203	+0.664	<.001	<.001	3	7
STOMACH	PARP2 →	+0.818	+0.467	<.001	.003	3	7
BLOOD_Myeloma	NRDE2 →	+1.244	+0.948	.002	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,891 associations by consensus.

RFX1 vs ZC3H14 — BONE

Explore this scatter interactively →