RFTN2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RFTN2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,261 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RFTN2-associated genes across cancer lineages are NUP62CL, PLXNC1, and COL6A2. Each is linked with RFTN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RFTN2-to-partner and partner-to-RFTN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFTN2 versus NUP62CL in UCEC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFTN2→partner) and Y-score (partner→RFTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNUP62CL →-1.098-0.449.001.00333
LSCCPLXNC1 →+0.542+0.312.001.00633
CCRCCCOL6A2 →+0.979+0.382.005.00333
LSCCDPT →+1.401+0.499<.001<.00133
LSCCCTSK →+1.055+0.382<.001<.00133
GBMKCNT2 →+0.770+0.317<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,261 associations by consensus.

RFTN2 vs NUP62CL — UCEC

Per-sample scatter of RFTN2 vs NUP62CL in UCEC (Pearson r = -0.49).

Explore this scatter interactively →

Exploration