RFTN2

Across TCGA patient cohorts, RFTN2 mutation is significantly associated with the RNA expression of many other genes, with 3,752 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RFTN2-associated genes across cancer lineages are RNU6-178P, RNA5SP413, and RNA5SP417. Each is linked with RFTN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RFTN2-to-partner and partner-to-RFTN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-178P grouped by RFTN2-low versus RFTN2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFTN2→partner) and Y-score (partner→RFTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-178P →	+0.817	+4.437	<.001	.002	3	3
UCEC	RNA5SP413 →	+1.021	+1.791	<.001	<.001	3	3
UCEC	RNA5SP417 →	+0.574	+2.351	<.001	<.001	3	3
LIHC	LINC01974 →	+0.163	+6.305	<.001	.001	3	2
UCEC	CWC25 →	+0.299	+2.375	.004	<.001	3	2
UCEC	ZNF280B →	+0.448	+1.818	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,752 associations by consensus.

RNU6-178P by RFTN2 expression — COAD

Explore this box plot interactively →