RFT1

Across TCGA cell cohorts, RFT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,982 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RFT1-associated GO terms across cancer lineages are Transcription by RNA polymerase I, Nucleosome disassembly, and Positive regulation of mitotic cell cycle phase transition. Each is linked with RFT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both RFT1-to-partner and partner-to-RFT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription by RNA polymerase I grouped by RFT1-low versus RFT1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFT1→partner) and Y-score (partner→RFT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Transcription by RNA polymerase I →	+0.110	+0.936	<.001	<.001	3	14
PANCREAS	Nucleosome disassembly →	+0.153	+0.799	<.001	.001	2	14
BREAST	Positive regulation of mitotic cell cycle phase transition →	+0.108	+0.852	<.001	<.001	3	13
BLOOD_Myeloma	Positive regulation of mRNA processing →	+0.123	+0.766	.001	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle checkpoint →	+0.141	+1.117	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle phase transition →	+0.083	+0.955	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,982 associations by consensus.

Transcription by RNA polymerase I by RFT1 expression — PANCREAS

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