RFPL4AP7

Across TCGA pan-cancer cohorts, RFPL4AP7 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated RFPL4AP7 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher RFPL4AP7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RFPL4AP7 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

LUSC, BRCA, and KIRP are the cancer types where RFPL4AP7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.306	0.677	.013	54	view →
BRCA	OS	Tertile	All	0.158	0.580	<.001	36	view →
KIRP	OS	Tertile	All	0.161	0.715	<.001	36	view →
HNSC	OS	Tertile	III,IV	0.222	0.679	.010	27	view →
KICH	DFS	Tertile	All	0.121	0.867	.023	24	view →
OV	DFS	Tertile	III,IV	0.713	0.150	.034	18	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RFPL4AP7–LUSC (OS)

Open the LUSC breakdown →