RFPL4AP5

Across TCGA pan-cancer cohorts, RFPL4AP5 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RFPL4AP5 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RFPL4AP5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RFPL4AP5 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUAD, UCEC, and KIRP are the cancer types where RFPL4AP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.266	0.835	<.001	108	view →
UCEC	OS	Tertile	All	0.761	0.928	<.001	108	view →
KIRP	OS	Tertile	All	0.449	0.888	<.001	90	view →
BRCA	DFS	Tertile	III,IV	0.093	0.880	<.001	54	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
BLCA	DFS	Tertile	All	0.214	0.522	.025	27	view →
SARC	OS	Tertile	All	0.534	0.843	.003	24	view →
LAML	DFS	Tertile	All	0.056	0.572	.001	18	view →
SKCM	DFS	Tertile	II,III,IV	1.000	0.249	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RFPL4AP5–LUAD (OS)

Open the LUAD breakdown →