RFPL4AP1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RFPL4AP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of RFPL4AP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RFPL4AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RFPL4AP1 is over-expressed in tumor.

HNSC and LUSC are the cancer types where RFPL4AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RFPL4AP1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCAllAll+0.020.0252view →
LUSCMaleAll+0.010.0451view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

RFPL4AP1–HNSC

Tumor-vs-normal expression box plot for RFPL4AP1 RNA in HNSC.

Open the HNSC breakdown →

Exploration