RFPL3

Across TCGA cell cohorts, RFPL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,004 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RFPL3-associated GO terms across cancer lineages are Vesicle targeting, to, from or within Golgi, Protein modification by small protein removal, and Regulation of stem cell population maintenance. Each is linked with RFPL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both RFPL3-to-partner and partner-to-RFPL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle targeting, to, from or within Golgi grouped by RFPL3-low versus RFPL3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL3→partner) and Y-score (partner→RFPL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Vesicle targeting, to, from or within Golgi →	+0.052	+0.043	.001	.009	3	5
UPPER_AERODIGESTIVE_TRACT	Protein modification by small protein removal →	+0.033	+0.042	.003	<.001	3	4
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.063	+0.071	.001	.003	3	4
UPPER_AERODIGESTIVE_TRACT	DNA integrity checkpoint signaling →	+0.055	+0.042	.005	<.001	3	4
LUNG_SCLC	Positive regulation of DNA metabolic process →	+0.040	+0.072	.005	.001	3	4
OVARY	Renal system process →	-0.073	-0.024	.002	.008	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,004 associations by consensus.

Vesicle targeting, to, from or within Golgi by RFPL3 expression — BLOOD_Lymphoma

Explore this box plot interactively →