RFPL2

Across TCGA cell cohorts, RFPL2 mutation is significantly associated with the mutation status of many other genes, with 97 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RFPL2-associated genes across cancer lineages are EPB41L4A, ZNF813, and DCAF12. Each is linked with RFPL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RFPL2-to-partner and partner-to-RFPL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPB41L4A grouped by RFPL2-low versus RFPL2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFPL2→partner) and Y-score (partner→RFPL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	EPB41L4A →	+5.066	+4.502	.007	.007	1	2
SOFT_TISSUE	ZNF813 →	+5.066	+4.502	.007	.007	1	2
SOFT_TISSUE	DCAF12 →	+5.066	+4.502	.007	.007	1	2
SOFT_TISSUE	ZNF132 →	+5.066	+4.502	.007	.007	1	1
SOFT_TISSUE	ADAMDEC1 →	+5.066	+4.502	.007	.007	1	1
SOFT_TISSUE	SLC44A5 →	+5.066	+4.502	.007	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

EPB41L4A by RFPL2 expression — SOFT_TISSUE

Explore this box plot interactively →