RFNG

Across TCGA patient cohorts, RFNG protein abundance is significantly associated with the RNA expression of many other genes, with 1,416 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RFNG-associated genes across cancer lineages are CALB2, PDE4DIP, and LMO3. Each is linked with RFNG in more than 1 cancer types. Because this analysis shows association rather than direction, both RFNG-to-partner and partner-to-RFNG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFNG versus CALB2 in OV, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFNG→partner) and Y-score (partner→RFNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CALB2 →	+1.864	+0.346	.003	.004	3	2
GBM	PDE4DIP →	-1.947	-0.600	<.001	<.001	3	2
GBM	LMO3 →	-4.005	-0.600	<.001	<.001	3	2
LUAD	SLCO4A1 →	+1.713	+0.390	.001	<.001	3	1
LUAD	COTL1 →	+0.746	+0.474	<.001	<.001	3	1
LUAD	AP3B2 →	-0.518	-0.411	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,416 associations by consensus.

RFNG vs CALB2 — OV

Explore this scatter interactively →