RFNG

Across TCGA cell cohorts, RFNG mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RFNG-associated genes across cancer lineages are KIR3DL1, OR10W1, and DIRAS2. Each is linked with RFNG in more than 1 cancer types. Because this analysis shows association rather than direction, both RFNG-to-partner and partner-to-RFNG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIR3DL1 grouped by RFNG-low versus RFNG-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFNG→partner) and Y-score (partner→RFNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KIR3DL1 →	+0.026	+4.276	.004	.007	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+4.977	.002	.007	3	1
BLOOD_Leukemia	DIRAS2 →	+0.116	+4.087	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

KIR3DL1 by RFNG expression — BLOOD_Leukemia

Explore this box plot interactively →