Across TCGA cell cohorts, RFLNB RNA expression is significantly associated with the go_rna of many other GO terms, with 5,087 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RFLNB-associated GO terms across cancer lineages are Negative regulation of bone mineralization involved in bone maturation, Negative regulation of chondrocyte development, and Peptidyl-lysine oxidation. Each is linked with RFLNB in more than 16 cancer types. Because this analysis shows association rather than direction, both RFLNB-to-partner and partner-to-RFLNB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RFLNB→partner) and Y-score (partner→RFLNB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of bone mineralization involved in bone maturation →	+2.110	+3.178	<.001	<.001	3	17
BLOOD_Myeloma	Negative regulation of chondrocyte development →	+1.726	+3.274	<.001	<.001	3	14
URINARY_TRACT	Peptidyl-lysine oxidation →	+1.276	+1.695	<.001	.007	3	12
BLOOD_Lymphoma	Regulation of chondrocyte development →	+1.099	+2.871	<.001	<.001	3	12
BREAST	Regulation of cell-substrate junction organization →	+0.075	+1.952	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Ossification involved in bone maturation →	-0.273	-2.693	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,087 associations by consensus.

Exploration

RFLNB survival (RNA) · tumor vs normal (RNA) · all RFLNB data types