RFKP2

Across TCGA pan-cancer cohorts, RFKP2 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RFKP2 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RFKP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RFKP2 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

PAAD, UCEC, and THCA are the cancer types where RFKP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Tertile	All	0.068	0.484	<.001	72	view →
UCEC	OS	Tertile	All	0.424	0.686	<.001	66	view →
THCA	OS	Tertile	II,III,IV	0.782	0.967	<.001	27	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →
LAML	DFS	Tertile	All	0.185	0.596	.016	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
SKCM	OS	Tertile	III,IV	0.289	0.839	.003	9	view →
THYM	DFS	Tertile	II,III,IV	0.174	0.734	.049	9	view →
SARC	OS	Tertile	All	0.140	0.596	.006	6	view →
HNSC	OS	Tertile	All	0.676	0.348	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RFKP2–PAAD (DFS)

Open the PAAD breakdown →