RFC5P1

Across TCGA pan-cancer cohorts, RFC5P1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RFC5P1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RFC5P1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RFC5P1 expression acts as an unfavorable survival marker, although some lineages such as LAML and HNSC show a favorable association.

UVM, KICH, and SKCM are the cancer types where RFC5P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.104	0.858	<.001	99	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
SKCM	OS	Tertile	All	0.639	0.788	.009	30	view →
READ	OS	Tertile	IV	0.111	0.893	<.001	27	view →
CESC	DFS	Tertile	All	0.685	0.828	.010	24	view →
ESCA	DFS	Tertile	All	0.148	0.673	.040	18	view →
LAML	DFS	Tertile	All	0.868	0.543	.026	18	view →
KIRC	DFS	Tertile	IV	0.334	0.640	.016	18	view →
HNSC	OS	Tertile	All	0.895	0.738	.018	18	view →
PCPG	DFS	Tertile	All	0.161	0.819	.004	18	view →
STAD	OS	Tertile	II,III,IV	0.400	0.600	.032	15	view →
THCA	OS	Tertile	II,III,IV	0.871	0.985	.010	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RFC5P1–UVM (OS)

Open the UVM breakdown →