RFC5

Across TCGA patient cohorts, RFC5 protein abundance is significantly associated with the RNA expression of many other genes, with 19,903 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RFC5-associated genes across cancer lineages are CDKN3, GINS1, and CENPI. Each is linked with RFC5 in more than 8 cancer types. Because this analysis shows association rather than direction, both RFC5-to-partner and partner-to-RFC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFC5 versus CDKN3 in UCEC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFC5→partner) and Y-score (partner→RFC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDKN3 →	+1.256	+0.393	<.001	<.001	3	9
UCEC	GINS1 →	+1.280	+0.446	<.001	<.001	3	9
LUAD	CENPI →	+1.161	+0.351	<.001	<.001	3	9
UCEC	ASF1B →	+1.214	+0.303	<.001	<.001	3	9
UCEC	NEIL3 →	+1.157	+0.401	<.001	<.001	3	9
UCEC	NCAPG →	+1.362	+0.357	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,903 associations by consensus.

RFC5 vs CDKN3 — UCEC

Explore this scatter interactively →