REXO5

Across TCGA patient cohorts, REXO5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,743 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible REXO5-associated genes across cancer lineages are TREM1, MEFV, and CSF3R. Each is linked with REXO5 in more than 4 cancer types. Because this analysis shows association rather than direction, both REXO5-to-partner and partner-to-REXO5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REXO5 versus TREM1 in PDAC, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REXO5→partner) and Y-score (partner→REXO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TREM1 →	-0.998	-0.840	<.001	<.001	3	5
HNSC	MEFV →	-0.649	-0.725	<.001	<.001	3	4
UCEC	CSF3R →	-1.155	-0.741	<.001	<.001	3	4
HNSC	BCL2A1 →	-1.771	-1.040	<.001	<.001	3	4
UCEC	CLEC4E →	-1.286	-0.755	<.001	<.001	3	4
PDAC	FPR2 →	-1.131	-0.709	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,743 associations by consensus.

REXO5 vs TREM1 — PDAC

Explore this scatter interactively →