REXO5

Across TCGA cell cohorts, REXO5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,508 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible REXO5-associated GO terms across cancer lineages are DNA synthesis involved in DNA repair, Meiotic cell cycle process, and Nuclear division. Each is linked with REXO5 in more than 15 cancer types. Because this analysis shows association rather than direction, both REXO5-to-partner and partner-to-REXO5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA synthesis involved in DNA repair grouped by REXO5-low versus REXO5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REXO5→partner) and Y-score (partner→REXO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA synthesis involved in DNA repair →	+0.101	+1.132	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Meiotic cell cycle process →	+0.071	+0.782	.004	.009	3	16
SKIN	Nuclear division →	+0.088	+1.042	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Meiotic nuclear division →	+0.073	+0.980	.001	<.001	3	15
SKIN	Mitotic sister chromatid segregation →	+0.115	+1.181	<.001	<.001	3	15
SKIN	Sister chromatid segregation →	+0.111	+1.181	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,508 associations by consensus.

DNA synthesis involved in DNA repair by REXO5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →