REXO4

Across TCGA patient cohorts, REXO4 mutation is significantly associated with the RNA expression of many other genes, with 2,687 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REXO4-associated genes across cancer lineages are RN7SL447P, RNU1-17P, and TRAJ57. Each is linked with REXO4 in more than 1 cancer types. Because this analysis shows association rather than direction, both REXO4-to-partner and partner-to-REXO4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL447P grouped by REXO4-low versus REXO4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REXO4→partner) and Y-score (partner→REXO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL447P →	+0.230	+5.201	<.001	.007	3	2
CESC	RNU1-17P →	+0.378	+5.103	<.001	.008	3	2
SKCM	TRAJ57 →	+0.774	+5.362	<.001	.005	3	2
SKCM	RNU6-1111P →	+0.370	+4.979	<.001	.009	3	2
COAD	RPL12P49 →	+0.497	+5.246	.001	<.001	3	2
BLCA	RNU6-921P →	+0.423	+5.038	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,687 associations by consensus.

RN7SL447P by REXO4 expression — CESC

Explore this box plot interactively →