REXO4

Across TCGA cell cohorts, REXO4 protein abundance is significantly associated with the RNA expression of many other genes, with 3,500 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible REXO4-associated genes across cancer lineages are ITPK1, EXD2, and PNPO. Each is linked with REXO4 in more than 7 cancer types. Because this analysis shows association rather than direction, both REXO4-to-partner and partner-to-REXO4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REXO4 versus ITPK1 in BLOOD_Lymphoma, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REXO4→partner) and Y-score (partner→REXO4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ITPK1 →	+1.729	+1.553	<.001	<.001	3	8
OVARY	EXD2 →	+0.675	+1.685	.002	.006	3	4
LUNG_SCLC	PNPO →	+0.909	+1.258	.001	.001	3	4
BLOOD_Lymphoma	RETSAT →	+1.111	+1.084	.001	.003	2	5
BLOOD_Leukemia	FBXW4 →	+0.659	+0.788	.001	<.001	3	4
SKIN	FSD1 →	-1.605	-0.890	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,500 associations by consensus.

REXO4 vs ITPK1 — BLOOD_Lymphoma

Explore this scatter interactively →