REXO2

Across TCGA patient cohorts, REXO2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,204 significant associations in total. GBM shows the largest number of these associations.

The most reproducible REXO2-associated genes across cancer lineages are ARCN1, FANCI, and SPAG5. Each is linked with REXO2 in more than 5 cancer types. Because this analysis shows association rather than direction, both REXO2-to-partner and partner-to-REXO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REXO2 versus ARCN1 in OV, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REXO2→partner) and Y-score (partner→REXO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARCN1 →	+0.545	+0.382	<.001	<.001	3	6
HNSC	FANCI →	-1.073	-0.315	<.001	<.001	3	5
UCEC	SPAG5 →	-0.934	-0.331	.001	.002	3	5
OV	STT3A →	+0.567	+0.344	<.001	<.001	3	5
OV	SRPRA →	+0.476	+0.327	<.001	<.001	3	5
OV	APLP2 →	+0.692	+0.366	.002	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,204 associations by consensus.

REXO2 vs ARCN1 — OV

Explore this scatter interactively →