REXO2

Across TCGA patient cohorts, REXO2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REXO2-associated genes across cancer lineages are Erythrocytes, Pericytes, and Basophils. Each is linked with REXO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both REXO2-to-partner and partner-to-REXO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by REXO2-low versus REXO2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REXO2→partner) and Y-score (partner→REXO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.044	+2.818	.001	.035	3	1
UCEC	Pericytes →	+0.038	+2.113	.009	.024	3	1
UCEC	Basophils →	+0.270	+3.169	.003	.020	2	1
UCEC	Endothelial cells →	-0.042	-3.127	.042	.020	1	1
UCEC	MEP →	+0.034	+3.180	.024	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Erythrocytes by REXO2 expression — UCEC

Explore this box plot interactively →