REXO2

Across TCGA cell cohorts, REXO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,107 significant associations in total. BONE shows the largest number of these associations.

The most reproducible REXO2-associated GO terms across cancer lineages are Ether catabolic process, Glycerol ether catabolic process, and Platelet activating factor catabolic process. Each is linked with REXO2 in more than 12 cancer types. Because this analysis shows association rather than direction, both REXO2-to-partner and partner-to-REXO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ether catabolic process grouped by REXO2-low versus REXO2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REXO2→partner) and Y-score (partner→REXO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Ether catabolic process →	+0.189	+1.410	<.001	<.001	3	13
BREAST	Glycerol ether catabolic process →	+0.189	+1.410	<.001	<.001	3	13
BREAST	Platelet activating factor catabolic process →	+0.189	+1.410	<.001	<.001	3	13
LIVER	Regulation of protein K48-linked ubiquitination →	+0.132	+1.032	.009	<.001	1	13
BONE	Positive regulation of early endosome to late endosome transport →	+0.171	+1.412	<.001	<.001	3	11
BONE	Regulation of early endosome to late endosome transport →	+0.148	+1.400	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,107 associations by consensus.

Ether catabolic process by REXO2 expression — BREAST

Explore this box plot interactively →