Across TCGA pan-cancer cohorts, REXO1L8P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of REXO1L8P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where REXO1L8P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types REXO1L8P is over-expressed in tumor.
HNSC and STAD are the cancer types where REXO1L8P tumor–normal differential expression is most reproducible.