Across TCGA pan-cancer cohorts, REXO1L1P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated REXO1L1P data layer compared with 4 for mutation status.
The strongest signal is observed in kidney chromophobe (KICH), where higher REXO1L1P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated REXO1L1P expression acts as an unfavorable survival marker, although some lineages such as OV and HNSC show a favorable association.
KICH, LIHC, and COAD are the cancer types where REXO1L1P RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.