REXO1L1P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, REXO1L1P Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated REXO1L1P data layer compared with 11 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher REXO1L1P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated REXO1L1P expression acts as an unfavorable survival marker.

LIHC, SKCM, and UCEC are the cancer types where REXO1L1P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LIHCOSMedianAll0.0930.783<.00130view →
SKCMOSMedianAll0.1930.783<.00112view →
UCECOSMedianIV0.2310.592.0366view →
ESCADFSMedianII,III,IV0.0820.495.0026view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration