RETREG3

Across TCGA patient cohorts, RETREG3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,382 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RETREG3-associated proteins across cancer lineages are DHX8, HEXIM1, and UBE2Z. Each is linked with RETREG3 in more than 5 cancer types. Because this analysis shows association rather than direction, both RETREG3-to-partner and partner-to-RETREG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RETREG3 versus DHX8 in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RETREG3→partner) and Y-score (partner→RETREG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX8 →	+0.267	+0.463	<.001	<.001	3	6
LSCC	HEXIM1 →	+0.399	+0.382	<.001	<.001	3	5
OV	UBE2Z →	+0.219	+0.336	<.001	.001	3	5
BRCA	NPEPPS →	+0.330	+0.547	<.001	<.001	3	4
BRCA	RRBP1 →	-0.486	-0.510	<.001	<.001	3	4
LSCC	SEC11C →	-0.972	-0.300	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,382 associations by consensus.

RETREG3 vs DHX8 — LSCC

Explore this scatter interactively →