RETREG3

Across TCGA cell cohorts, RETREG3 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RETREG3-associated genes across cancer lineages are ZPBP2, UGT2B28, and PTH. Each is linked with RETREG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RETREG3-to-partner and partner-to-RETREG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZPBP2 grouped by RETREG3-low versus RETREG3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RETREG3→partner) and Y-score (partner→RETREG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ZPBP2 →	+0.097	+4.930	<.001	.008	3	1
BLOOD_Lymphoma	UGT2B28 →	+0.807	+4.192	<.001	.003	3	1
BLOOD_Lymphoma	PTH →	+0.013	+4.662	<.001	.003	3	1
BLOOD_Lymphoma	PRKACG →	+0.030	+4.070	<.001	.004	3	1
BLOOD_Lymphoma	TPD52L3 →	+0.057	+4.070	<.001	.004	3	1
BLOOD_Lymphoma	RNF186 →	+0.384	+4.321	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

ZPBP2 by RETREG3 expression — SOFT_TISSUE

Explore this box plot interactively →