RETREG2

Across TCGA cell cohorts, RETREG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,824 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RETREG2-associated GO terms across cancer lineages are Endosomal transport, Protein polyubiquitination, and Lysosomal transport. Each is linked with RETREG2 in more than 14 cancer types. Because this analysis shows association rather than direction, both RETREG2-to-partner and partner-to-RETREG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by RETREG2-low versus RETREG2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RETREG2→partner) and Y-score (partner→RETREG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.058	+0.724	.002	.004	3	15
SOFT_TISSUE	Protein polyubiquitination →	+0.042	+0.630	<.001	<.001	3	14
LUNG_SCLC	Lysosomal transport →	+0.054	+0.529	<.001	.002	3	14
LARGE_INTESTINE	Cytosolic transport →	+0.053	+0.457	<.001	.002	3	13
KIDNEY	Peptidyl-serine phosphorylation →	+0.094	+0.849	.001	<.001	3	13
KIDNEY	Peptidyl-serine modification →	+0.092	+0.782	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,824 associations by consensus.

Endosomal transport by RETREG2 expression — UPPER_AERODIGESTIVE_TRACT

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