RETREG1

Across TCGA cell cohorts, RETREG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,077 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RETREG1-associated GO terms across cancer lineages are Protein sumoylation, Respiratory electron transport chain, and Proton transmembrane transport. Each is linked with RETREG1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RETREG1-to-partner and partner-to-RETREG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein sumoylation grouped by RETREG1-low versus RETREG1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RETREG1→partner) and Y-score (partner→RETREG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein sumoylation →	+0.046	+0.841	.003	.003	3	8
PANCREAS	Respiratory electron transport chain →	+0.066	+1.265	<.001	<.001	3	8
LUNG_SCLC	Proton transmembrane transport →	+0.080	+1.781	<.001	.001	3	8
LUNG_NSCLC_LUSC	Cap-dependent translational initiation →	+0.111	+1.932	<.001	<.001	3	7
BONE	Epithelial cell fate commitment →	-0.191	-1.355	.002	.004	2	8
STOMACH	Mitochondrial electron transport, cytochrome c to oxygen →	+0.092	+1.611	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,077 associations by consensus.

Protein sumoylation by RETREG1 expression — PANCREAS

Explore this box plot interactively →