RETREG1

Across TCGA cell cohorts, RETREG1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RETREG1-associated genes across cancer lineages are OR1L3, OR10W1, and FIGLA. Each is linked with RETREG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RETREG1-to-partner and partner-to-RETREG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by RETREG1-low versus RETREG1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RETREG1→partner) and Y-score (partner→RETREG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR1L3 →	+0.012	+5.643	<.001	.002	3	1
BREAST	OR10W1 →	+0.010	+4.781	<.001	.003	3	1
BREAST	FIGLA →	+0.208	+4.421	.002	.004	3	1
LARGE_INTESTINE	KRTAP13-2 →	+0.017	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CCDC195 →	+0.065	+4.467	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR11H1 →	+0.025	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR1L3 by RETREG1 expression — BLOOD_Lymphoma

Explore this box plot interactively →