RETNLB

Across TCGA patient cohorts, RETNLB mutation is significantly associated with the RNA expression of many other genes, with 598 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RETNLB-associated genes across cancer lineages are MIR4529, RNA5SP412, and PSAT1P4. Each is linked with RETNLB in more than 2 cancer types. Because this analysis shows association rather than direction, both RETNLB-to-partner and partner-to-RETNLB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4529 grouped by RETNLB-low versus RETNLB-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RETNLB→partner) and Y-score (partner→RETNLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR4529 →	+0.284	+3.370	.004	.008	3	3
UCEC	RNA5SP412 →	+0.578	+2.481	.002	.006	3	2
LUSC	PSAT1P4 →	+0.165	+3.171	<.001	.006	3	2
LUSC	GAPDHP19 →	+0.228	+3.760	<.001	.001	3	2
COAD	RN7SL575P →	+0.466	+5.017	.009	.009	3	2
UCEC	MRPS11 →	+0.501	+3.212	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 598 associations by consensus.

MIR4529 by RETNLB expression — LUSC

Explore this box plot interactively →