RESF1

Across TCGA pan-cancer cohorts, RESF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RESF1 data layer compared with 19 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher RESF1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RESF1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

GBM, PDAC, and HNSC are the cancer types where RESF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.515	1.000	.007	4	view →
PDAC	OS	Quartile	II,III,IV	0.490	0.889	.038	3	view →
HNSC	OS	Median	III,IV	0.833	0.414	.038	1	view →
LUAD	OS	Quartile	II,III,IV	0.782	1.000	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RESF1–GBM (DFS)

Open the GBM breakdown →