RESF1

Across TCGA cell cohorts, RESF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,283 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RESF1-associated GO terms across cancer lineages are Transposable element silencing by heterochromatin formation, Chromatin looping, and Protein sumoylation. Each is linked with RESF1 in more than 10 cancer types. Because this analysis shows association rather than direction, both RESF1-to-partner and partner-to-RESF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transposable element silencing by heterochromatin formation grouped by RESF1-low versus RESF1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RESF1→partner) and Y-score (partner→RESF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Transposable element silencing by heterochromatin formation →	+0.157	+1.502	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Chromatin looping →	+0.082	+0.828	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Protein sumoylation →	+0.073	+1.246	<.001	<.001	3	9
LUNG_SCLC	Regulation of centrosome cycle →	+0.076	+0.928	<.001	<.001	3	9
BLOOD_Myeloma	Regulation of centriole elongation →	+0.074	+0.748	.004	.006	3	9
BLOOD_Lymphoma	Subtelomeric heterochromatin formation →	+0.075	+0.803	.002	.006	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,283 associations by consensus.

Transposable element silencing by heterochromatin formation by RESF1 expression — OVARY

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