RESF1

Across TCGA cell cohorts, RESF1 mutation is significantly associated with the RNA expression of many other genes, with 116 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RESF1-associated genes across cancer lineages are GAGE12H, CUX2, and LBX1. Each is linked with RESF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RESF1-to-partner and partner-to-RESF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12H grouped by RESF1-low versus RESF1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RESF1→partner) and Y-score (partner→RESF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	GAGE12H →	+0.058	+3.432	.007	.008	3	2
PANCREAS	CUX2 →	+0.172	+3.807	<.001	.003	3	1
PANCREAS	LBX1 →	+0.196	+3.731	.001	.002	3	1
PANCREAS	C10orf90 →	+0.163	+3.380	<.001	.008	3	1
PANCREAS	SALL3 →	+0.025	+4.807	<.001	<.001	3	1
PANCREAS	FRRS1L →	+0.208	+3.357	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

GAGE12H by RESF1 expression — STOMACH

Explore this box plot interactively →