RESF1

Across TCGA cell cohorts, RESF1 mutation is significantly associated with the mutation status of many other genes, with 3,108 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RESF1-associated genes across cancer lineages are RPTOR, CRACDL, and PLEC. Each is linked with RESF1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RESF1-to-partner and partner-to-RESF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPTOR grouped by RESF1-low versus RESF1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RESF1→partner) and Y-score (partner→RESF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	RPTOR →	+4.139	+2.935	.007	.007	1	5
OVARY	CRACDL →	+5.415	+5.415	.004	.004	1	5
LARGE_INTESTINE	PLEC →	+1.056	+2.539	.005	.005	1	5
PANCREAS	ITSN1 →	+4.139	+2.935	.007	.007	1	4
PANCREAS	TG →	+2.969	+2.777	.005	.005	1	4
PANCREAS	SH2D3C →	+4.139	+2.935	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,108 associations by consensus.

RPTOR by RESF1 expression — PANCREAS

Explore this box plot interactively →