RERG

Across TCGA patient cohorts, RERG protein abundance is significantly associated with the RNA expression of many other genes, with 13,929 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RERG-associated genes across cancer lineages are RERG-AS1, CKAP2L, and BUB1. Each is linked with RERG in more than 6 cancer types. Because this analysis shows association rather than direction, both RERG-to-partner and partner-to-RERG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RERG versus RERG-AS1 in CCRCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RERG→partner) and Y-score (partner→RERG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RERG-AS1 →	+1.475	+0.502	<.001	<.001	3	7
LUAD	CKAP2L →	-0.888	-0.492	<.001	<.001	3	6
BRCA	BUB1 →	-1.058	-0.673	<.001	<.001	3	6
BRCA	TNS2 →	+0.809	+0.483	<.001	.004	3	6
BRCA	STIL →	-0.720	-0.649	.001	.001	3	6
CCRCC	EDNRB →	+1.153	+0.368	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,929 associations by consensus.

RERG vs RERG-AS1 — CCRCC

Explore this scatter interactively →