RERG

Across TCGA cell cohorts, RERG RNA expression is significantly associated with the go_rna of many other GO terms, with 1,486 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RERG-associated GO terms across cancer lineages are Negative regulation of chondrocyte differentiation, Outer mitochondrial membrane organization, and Purine ribonucleoside triphosphate metabolic process. Each is linked with RERG in more than 5 cancer types. Because this analysis shows association rather than direction, both RERG-to-partner and partner-to-RERG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chondrocyte differentiation grouped by RERG-low versus RERG-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RERG→partner) and Y-score (partner→RERG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of chondrocyte differentiation →	-0.139	-1.216	.001	<.001	3	5
SKIN	Outer mitochondrial membrane organization →	+0.080	+0.909	<.001	<.001	3	5
KIDNEY	Purine ribonucleoside triphosphate metabolic process →	+0.060	+0.936	.002	.005	2	6
BREAST	Vesicle budding from membrane →	+0.051	+2.143	.006	.001	3	5
BREAST	Endosome organization →	+0.044	+1.973	.005	.001	3	5
CNS	Heart trabecula formation →	-0.137	-0.700	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,486 associations by consensus.

Negative regulation of chondrocyte differentiation by RERG expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →