RERG

Across TCGA cell cohorts, RERG mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RERG-associated genes across cancer lineages are MYF6 and WFIKKN2. Each is linked with RERG in more than 1 cancer types. Because this analysis shows association rather than direction, both RERG-to-partner and partner-to-RERG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF6 grouped by RERG-low versus RERG-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RERG→partner) and Y-score (partner→RERG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYF6 →	+0.169	+4.705	<.001	.003	3	1
BLOOD_Leukemia	WFIKKN2 →	+0.020	+4.954	<.001	.001	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MYF6 by RERG expression — BLOOD_Leukemia

Explore this box plot interactively →