RERE

Across TCGA patient cohorts, RERE protein abundance is significantly associated with the RNA expression of many other genes, with 10,325 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RERE-associated genes across cancer lineages are PHC1, LRRC47, and SLC35E2B. Each is linked with RERE in more than 4 cancer types. Because this analysis shows association rather than direction, both RERE-to-partner and partner-to-RERE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RERE versus PHC1 in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RERE→partner) and Y-score (partner→RERE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PHC1 →	+0.604	+0.357	<.001	<.001	3	5
LSCC	LRRC47 →	+0.596	+0.294	<.001	.001	3	5
BRCA	SLC35E2B →	+0.641	+0.272	<.001	<.001	3	5
LSCC	THAP3 →	+0.540	+0.328	<.001	<.001	3	5
GBM	USP48 →	+0.494	+0.429	<.001	<.001	3	5
LSCC	MECR →	+0.535	+0.295	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,325 associations by consensus.

RERE vs PHC1 — GBM

Explore this scatter interactively →