RERE

Across TCGA cell cohorts, RERE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,979 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RERE-associated GO terms across cancer lineages are Positive regulation of TORC2 signaling, Regulation of DNA repair, and Regulation of nucleotide-excision repair. Each is linked with RERE in more than 14 cancer types. Because this analysis shows association rather than direction, both RERE-to-partner and partner-to-RERE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of TORC2 signaling grouped by RERE-low versus RERE-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RERE→partner) and Y-score (partner→RERE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of TORC2 signaling →	+0.095	+1.395	<.001	<.001	3	15
SOFT_TISSUE	Regulation of DNA repair →	+0.074	+1.045	<.001	<.001	3	15
OVARY	Regulation of nucleotide-excision repair →	+0.122	+1.274	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.064	+1.098	<.001	<.001	3	14
KIDNEY	Nucleus localization →	+0.061	+0.830	.003	.002	3	14
STOMACH	Positive regulation of double-strand break repair →	+0.096	+1.239	.006	.007	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,979 associations by consensus.

Positive regulation of TORC2 signaling by RERE expression — BLOOD_Lymphoma

Explore this box plot interactively →